Fluciclovine PET imaging is the most sensitive imaging modality we have to date that is United States Food and Drug Administration (FDA) approved and available for widespread use. Fluciclovine is a synthetic amino acid that is uptaken by amino acid transporters that are upregulated in many cancer cells, including prostate cancer. A key advantage of […]
Recently, those of us who treat prostate cancer have been comfortable with testing for Breast Cancer Gene 2 (BRCA2) and acting on the results. It’s now time we took a slightly deeper dive into this gene and how knowing more can help us counsel our patients better and design better clinical trials. With two poly […]
Coronaviruses (CoV) are a group of viruses whose antigens are expressed on their membranes in a characteristic “crown like” appearance, hence giving them their name (from Latin corona [crown]). Since their initial discovery in 1965,1 about 46 species have been identified in animals and humans with 2 species, namely, severe acute respiratory syndrome (SARS)-CoV-1 and […]
As the world continues to be affected by the COVID-19 pandemic, severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), prostate cancer awareness may seem like something that could be forgotten this year. Just today in the state where I live, Illinois, we learned of 1,880 new cases of coronavirus yesterday, with over 180,000 deaths in the United States […]
Early and accurate localization of lesions in patients with biochemical recurrence (BCR) of prostate cancer may guide salvage therapy decisions. The present study, 18F-Fluciclovine PET/CT in biochemicAL reCurrence Of Prostate caNcer (FALCON; NCT02578940), aimed to evaluate the effect of 18F-fluciclovine on management of men with BCR of prostate cancer.
A BRCA2 prostate cancer cluster region (PCCR) was recently proposed (c.7914 to 3′) wherein pathogenic variants (PVs) are associated with higher prostate cancer (PCa) risk than PVs elsewhere in the BRCA2 gene.
The global COVID-19 health and economic crisis has forced people to adopt challenging rules of social distancing and self-isolation. Health care staff has been advised to change working routines to keep themselves and their patients safe.
Objective: The role of pelvic lymph node dissection (PLND) is still debated in patients with N3 stage penile cancer. In Denmark this subgroup of patients is in general managed with an inguinal lymphadenectomy (ILND) and adjuvant chemoradiation and PLND is not offered as a standard.
Current serum tumor markers (STMs) for testicular germ cell tumor (GCT) are limited by low sensitivity. Growing evidence supports the use of circulating miR-371a-3p as a superior marker for malignant (viable) GCT management.
Renal cell carcinoma (RCC) incidence is increasing worldwide. A high proportion of individuals are asymptomatic at diagnosis, but RCC has a high mortality rate. These facts suggest that RCC meets some of the criteria for screening, and a new analysis shows that screening for RCC could potentially be cost-effective.
