- In some cases, this type of therapy increases the invasiveness and metastasis of kidney tumors.
- The study led by IDIBELL and the ICO identifies a biomarker that could predict the malignant response of patients to therapy.
San Francisco, CA (UroToday.com) — Angiogenesis is the process by which tumors create new blood vessels that will provide them the nutrients to continue growing. Antiangiogenic drugs specifically block this process. This type of therapy usually has good short-term results, reducing tumor growth. However, several studies suggest that these treatments increase the invasiveness of tumors, and promote more aggressive behavior, inducing a poor prognosis. Studies with animal models have attempted to decipher the molecular mechanisms involved in this discrepancy, but many questions remain unclear.