(Urotoday.com) The Global Society of Rare Genitourinary Tumors inaugural virtual summit included a presentation by Dr. Juanita Crook discussing the role of radiotherapy in the perioperative treatment of patients with penile carcinoma. As Dr. Crook notes, the main clinical problem is clinical node-positive penile cancer. Due to the low prevalence of penile cancer, clinical trials have not been performed to determine the optimum combination of surgery, radiotherapy, and chemotherapy. Additionally, there is no data available for contemporary radiation technology and chemo-radiotherapy techniques. Without good evidence, surgical therapy is regarded as the ‘standard of care’ for these patients.