Upper urinary tract urothelial carcinoma (UTUC) constituted 5-10% of urothelial carcinomas. The management of UTUC has significantly changed in the last decade with the introduction of neoadjuvant chemotherapy options and kidney-sparing surgery (KSS) as an alternative to radical nephroureterectomy (RNU). Studying the trends in incidence, management approaches, and survival outcomes from large-scale cancer registries can shed light on the impact of these advances.

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