(UroToday.com) At the European Association of Urology (EAU) 2021 Annual Meeting, Dr. Axel Heidenreich discussed when and how to perform lymphadenectomy for prostate cancer at the joint session of the EAU and the Confederacion Americana De Urologica. Dr. Heidenreich notes that the rationale of pelvic lymphadenectomy is to (i) identify micrometastatic spread to locoregional lymph nodes, (ii) assess risk of future progression, (iii) decide on the best individual approach for the patient (ie. surveillance versus adjuvant therapy), and (iv) improve oncological outcome in terms of progression and survival.