To date, research has focused less on prevention of lower urinary tract symptoms (LUTS) and more on identifying causes and phenotypes of LUTS. The impact of behavioral, psychological, and socioeconomic contributors to LUTS is understudied. To identify strategies for promoting bladder health and reducing LUTS in women, the National Institute of Diabetes and Digestive and Kidney Diseases supported the development of the Prevention of Lower Urinary Tract Symptoms (PLUS) Consortium. The mission of the PLUS consortium is to “identify promising strategies for promoting bladder health and reducing lower urinary tract symptoms and conditions in women throughout the lifespan”.1