(UroToday.com) The Society of Urologic Oncology (SUO) annual winter meeting included a kidney cancer session and a presentation by Dr. Jose Karam discussing updates to the new AUA guidelines for the evaluation and management of clinically localized sporadic renal masses.1,2 Dr. Karam noted that the methodology for this guideline is comparable to previous AUA guidelines, including a rigorous, evidence-based approach, extensive peer review, systematic review and meta-analysis, and multiple conference calls. The follow-up for clinically localized renal neoplasms guideline was published in 2013 and was merged with the renal mass and localized renal cancer guideline from 2017. For this amendment, a literature search retrieved studies published between July 2016 and October 2020, identifying 19 new studies.