(UroToday.com) The 2022 EAU Section of Oncological Urology (ESOU) Annual Meeting included a session on locally advanced and oligometastatic prostate cancer and a presentation by Dr. Mary-Ellen Taplin discussing neoadjuvant treatments before radical prostatectomy for high-risk prostate cancer. Dr. Taplin notes that ~15% of patients present with localized high-risk prostate cancer, which may be life-threatening to the patient based on 15-year prostate cancer-specific mortality rates as follows: