- Phase III VISION study with 177Lu-PSMA-617 met both primary endpoints, significantly improving overall survival (OS) and radiographic progression-free survival (rPFS) in patients with PSMA-positive metastatic castration-resistant prostate cancer1
- VISION trial findings to be presented at upcoming medical meeting, with regulatory submissions in the US and EU anticipated in 2021
- Novartis is committed to reimagining prostate cancer through targeted radioligand therapy with 177Lu-PSMA-617
- More than 15 dedicated early to late development and research programs underway to identify the next wave of radioligand therapies for cancer
San Francisco, CA (UroToday.com) — Novartis reported the first interpretable results of the Phase III VISION study evaluating the efficacy and safety of 177Lu-PSMA-617, a targeted radioligand therapy in patients with progressive PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) compared to best standard of care alone. The trial met both primary endpoints of overall survival and radiographic progression-free survival,1 helping to move closer to the ambition of becoming the targeted treatment for >80% of patients with advanced prostate cancer. The safety profile was consistent with data reported in previous clinical studies.1 Results from the VISION trial will be presented at an upcoming medical meeting and included in US and EU regulatory submissions.