Studies evaluating the association between peripheral blood leukocyte telomere length and testicular germ cell tumor (TGCT) risk have produced conflicting results.
Using available genotype data from the Testicular Cancer Consortium (TECAC), polygenic risk score (PRS) and mendelian randomization (MR) analyses of genetic variants previously associated with leukocyte telomere length were used to assess potential etiologic associations between telomere length and TGCT risk.