(UroToday.com) At the 2021 American Urological Association (AUA) Summer School session on the updates in the management of penile cancer, Dr. Andrea Necchi from IRCCS San Raffaele Hospital and Scientific Institute in Milan discussed the perioperative treatment of penile cancer. Dr. Necchi notes that the prognosis of penile cancer is predictable based on the importance of N and M stage, with the most clinically important stage, with regards to management decision-making, being the N stage as highlighted in the following figure: