(UroToday.com) The 2021 American Urological Association (AUA) Summer School session on Upper Tract Urothelial Carcinoma included a case-based discussion led by moderator Dr. Surena Matin who was joined by panelists Dr. Sima Porten and Dr. Vitaly Margulis. This case focused on the management of upper tract urothelial carcinoma in the setting of a previous cystectomy with neobladder urinary diversion. The patient was a 75-year-old male who previously underwent a radical cystectomy, bilateral pelvic lymphadenectomy with a Studer pouch for BCG refractory bladder CIS, final pathology pTispN0R0. Surveillance imaging demonstrated left hydronephrosis and a soft tissue lesion in the left ureter. His GFR had previously been 47, but had recently decreased to 22 in the setting of worsening Parkinson’s disease and dementia: