Introduction: Infertility is a significant public health problem that affects 13% to 18% of couples worldwide1 with the male factors either partially or mainly responsible for approximately 50% of the infertility cases.2 Semen analysis is the cornerstone for laboratory evaluation of male infertility and plays a vital role in understanding the cause of infertility.3 As a diagnostic test, conventional semen analysis allows for the detection of absolute cases of male infertility such as azoospermia. In addition, with repeated abnormal semen analyses results, men can be diagnosed as infertile and an approximate prognosis can be given. Furthermore, semen analysis may help predict natural conception and assist the clinicians in managing the couple’s infertility using assisted reproductive technology (ART).4