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Cancer-associated thrombosis is a condition where patients with active cancer have a higher risk of deep vein thrombosis and pulmonary embolism compared to the general population.1-2 Compared to patients without cancer-associated thrombosis, patients with cancer-associated thrombosis have a higher morbidity and mortality, higher likelihood of cancer progression, and increased health care costs.2-4 Specifically, patients with […]

Approval Based on Results From CLEAR/KEYNOTE-581 Trial Demonstrating KEYTRUDA Plus LENVIMA Significantly Reduced the Risk of Disease Progression or Death by 61%, With a Median Progression-Free Survival of Nearly Two Years Versus Nine Months for Sunitinib San Francisco, CA (UroToday.com) — Merck, known as MSD outside the United States and Canada, and Eisai announced that the […]

PYLARIFY AI is an FDA-cleared artificial intelligence platform developed to assist in standardized quantification of PSMA PET/CT scans San Francisco, CA (UroToday.com) — Lantheus Holdings, Inc., an established leader and fully integrated provider committed to innovative imaging diagnostics, targeted therapeutics, and artificial intelligence solutions to find, fight and follow serious medical conditions, announced that PYLARIFY AI™, […]

Background: Innovations in treatments, imaging, and molecular characterisation have improved outcomes for people with advanced prostate cancer; however, many aspects of clinical management are devoid of high-level evidence. At the Advanced Prostate Cancer Consensus Conference (APCCC) 2019, many of these topics were addressed, and consensus was not always reached. The results from clinical trials will […]

We aimed to review the trends and incidence of surgical intervention for adults with upper urinary tract stones in Ontario, Canada, and to hypothesize potential causes for the observed changes. We carried out a retrospective, population-based cohort study using administrative databases held at the Institute of Clinical Evaluative Sciences (IC/ES) to identify all adults (≥18 […]

Because of phenotypic overlap between monogenic urinary stone diseases (USD), gene-specific analyses can result in missed diagnoses. We used targeted next generation sequencing (tNGS), including known and candidate monogenic USD genes, to analyze suspected primary hyperoxaluria (PH) or Dent disease (DD) patients genetically unresolved (negative; N) after Sanger analysis of the known genes.

We aimed to examine the association between metabolic syndrome and the risk of kidney stone development in a large-scale community-based cohort. A total of 121,579 participants enrolled in the Taiwan Biobank were analyzed.

The burden of kidney stone disease (KSD) has risen, and several treatment options now exist. We wanted to evaluate the preference and treatment choices based on the information provided for management of hypothetical 8mm and 15mm renal stone, and factors that influenced their decision.

Background: Minimally invasive simple prostatectomy (MISP) and endoscopic enucleation of the prostate (EEP) are the two most commonly used methods for large benign prostatic hyperplasia (BPH), but it remains unclear which of the two is superior.

To assess the effects of posterior musculofascial reconstruction robotic-assisted laparoscopic prostatectomy (PR-RALP) compared to no posterior reconstruction during (S-RALP) for the treatment of clinically localized prostate cancer.