FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE): A Phase II Randomized Trial

FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE): A Phase II Randomized Trial Condition: Prostate Cancer Intervention: Radiation: Radiation Therapy Drug: Enzalutamide Drug: Abiraterone Drug: Docetaxel Purpose: This clinical trial will determine whether the addition of radiotherapy to standard of care first line systemic therapy improves objective progression-free survival rate (combined radiographic and clinical) at […]

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib in Patients With Metastatic Castration-Resistant Prostate Cancer

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib in Patients With Metastatic Castration-Resistant Prostate Cancer Condition: Prostate Cancer Intervention: Drug: Abemaciclib Drug: Abiraterone Acetate Drug: Prednisone Drug: Placebo Purpose: This study is being done to see how safe and effective abemaciclib is when given together with abiraterone […]

A Phase II Study of Palbociclib, A CDK4/6 Inhibitor, in Patients With Metastatic Castration-Resistant Prostate Cancer

A Phase II Study of Palbociclib, A CDK4/6 Inhibitor, in Patients With Metastatic Castration-Resistant Prostate Cancer Condition: Prostate Cancer Intervention: Drug: Palbociclib Purpose: The purpose of this study is to find out what effects a new drug, palbociclib, has on prostate cancer and will look at the side effects of treatment with palbociclib. The researchers […]

Randomized Phase IB/II Study of Enzalutamide With and Without Ribociclib in Patients With Metastatic Castrate Resistant, Chemotherapy Naïve Prostate Cancer That Retains RB Expression

Randomized Phase IB/II Study of Enzalutamide With and Without Ribociclib in Patients With Metastatic Castrate Resistant, Chemotherapy Naïve Prostate Cancer That Retains RB Expression Condition: Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone, Stage IV Prostate Cancer Intervention: Drug: Enzalutamide Drug: Ribociclib Purpose: This partially randomized phase IB/II trial studies the […]

Prostate Cancer, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.

The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis, risk stratification and workup, treatment options for localized disease, and management of recurrent and advanced disease for clinicians who treat patients with prostate cancer. The portions of the guidelines included herein focus on the roles of germline and somatic genetic testing, risk stratification with nomograms […]

Toronto General Hospital Physicians Presented Interim Clinical Study Results for MR-guided FLA Treatment of Low-intermediate Risk Localized Prostate Cancer at AdMeTech 4th Global Summit

The treatments in the study are being performed using CLS’s TRANBERG®|Thermal Therapy System, optimized for high-precision thermal ablation treatment. “The short term oncologic and functional outcomes for treatment of this group of patients is encouraging,” stated Dr. Sangeet Ghai, Vice Chief of Research and Abdominal Radiologist with the Toronto Joint Department of Medical Imaging (JDMI). […]

Desert Medical Imaging Doctors Presented Interim Clinical Study Results of MR-guided FLA Treatment of MR-visible Prostate Cancer at AdMeTech 4th Global Summit

The poster describes nine-year interim results from a clinical study regarding MR-guided Focal Laser Ablation treatment of low-intermediate-risk localized prostate cancer (NCT02243033). Some of the treatments in the clinical study have been performed using the TRANBERG® laser applicator non-cooled, optimized for high-precision thermal ablation treatment.  POSTER OVERVIEW Title: ”TRANSRECTALLY DELIVERED, OUTPATIENT MRI-GUIDED LASER FOCAL THERAPY […]

Could Surgical Experience of Adult Endourologist Overcome the Learning Curve of Retrograde Intrarenal Surgery in Children? – Beyond the Abstract

With the increase of the prevalence of pediatric urolithiasis (1-5%), retrograde intrarenal surgery (RIRS) is emerging as the preferred option for the management of stones in pediatric patients. Although the principles of RIRS developed in adults can be applied in children, also expert adult endourologists feel uncomfortable approaching young patients due to a long learning […]

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