The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis, risk stratification and workup, treatment options for localized disease, and management of recurrent and advanced disease for clinicians who treat patients with prostate cancer.

The portions of the guidelines included herein focus on the roles of germline and somatic genetic testing, risk stratification with nomograms and tumor multigene molecular testing, androgen deprivation therapy, secondary hormonal therapy, chemotherapy, and immunotherapy in patients with prostate cancer.

Journal of the National Comprehensive Cancer Network : JNCCN. 2019 May 01 [Epub]

James L Mohler, Emmanuel S Antonarakis, Andrew J Armstrong, Anthony V D’Amico, Brian J Davis, Tanya Dorff, James A Eastham, Charles A Enke, Thomas A Farrington, Celestia S Higano, Eric Mark Horwitz, Michael Hurwitz, Joseph E Ippolito, Christopher J Kane, Michael R Kuettel, Joshua M Lang, Jesse McKenney, George Netto, David F Penson, Elizabeth R Plimack, Julio M Pow-Sang, Thomas J Pugh, Sylvia Richey, Mack Roach, Stan Rosenfeld, Edward Schaeffer, Ahmad Shabsigh, Eric J Small, Daniel E Spratt, Sandy Srinivas, Jonathan Tward, Dorothy A Shead, Deborah A Freedman-Cass

1Roswell Park Comprehensive Cancer Center., 2The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins., 3Duke Cancer Institute., 4Dana-Farber/Brigham and Women’s Cancer Center., 5Mayo Clinic Cancer Center., 6City of Hope National Cancer Center., 7Memorial Sloan Kettering Cancer Center., 8Fred & Pamela Buffett Cancer Center., 9Prostate Health Education Network (PHEN)., 10Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance., 11Fox Chase Cancer Center., 12Yale Cancer Center/Smilow Cancer Hospital., 13Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine., 14UC San Diego Moores Cancer Center., 15University of Wisconsin Carbone Cancer Center., 16Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute., 17University of Alabama at Birmingham Comprehensive Cancer Center., 18Vanderbilt-Ingram Cancer Center., 19Moffitt Cancer Center., 20University of Colorado Cancer Center., 21St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center., 22UCSF Helen Diller Family Comprehensive Cancer Center., 23Robert H. Lurie Comprehensive Cancer Center of Northwestern University., 24The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute., 25University of Michigan Rogel Cancer Center., 26Stanford Cancer Institute., 27Huntsman Cancer Institute at the University of Utah; and., 28National Comprehensive Cancer Network.