New YAU working group on kidney transplantation

Nowadays, kidney transplantation (KT) is considered the best treatment option for patients with end-stage renal disease, with more than 20,000 KTs being performed each year in Europe. Given the epidemiological relevance and the clinical importance of chronic renal failure disease and KT, as well as, the fundamental role of the urologist in this field, a […]

APCCC 2021: What Can Meta-Analyses, Network Meta-Analyses and Subgroup Analyses Tell Us About Treatment Options: Pearls and Pitfalls

(UroToday.com) The first session of the Advanced Prostate Cancer Consensus Conference 2021 which was hosted virtually in the context of the COVID-19 pandemic focused on the management of patients with newly diagnosed metastatic hormone-sensitive prostate cancer. In this context, Dr. Claire Vale discussed analytic issues including the role of meta-analysis, network meta-analysis, and subgroup analyses to […]

APCCC 2021: DNA Repair Defect Aberrations – What Are the Differences Between Them and What Is the Impact on Patient Management?

(UroToday.com) The Advanced Prostate Cancer Consensus Conference 2021 virtual meeting session discussing PARP inhibitors and beyond included a presentation by Dr. Johann De Bono regarding differences between DNA repair defect aberrations and the impact on patient management. Dr. De Bono started by highlighting that >20-30% of advanced prostate cancer patients have DNA repair defect mutations, including […]

APCCC 2021: Contagious Enthusiasm in PSMA-Driven Therapeutics

(UroToday.com) The Advanced Prostate Cancer Consensus Conference 2021 virtual meeting session discussing PSMA in diagnostics and therapy included a presentation by Dr. Eleni Efstathiou discussing the contagious enthusiasm of PSMA-driven therapeutics. Dr. Efstathiou notes that the VISION study outcomes1 have set the bar high, with 177Lu-PSMA-617 targeted radioligand therapy improving overall survival (OS), radiographic PFS, and […]

APCCC 2021: Who Needs Germline Testing for Prostate Cancer and What Should Be Tested?

(UroToday.com) In this session, Dr. Dana Rathkopf discusses germline testing recommendations for men with prostate cancer. Guidelines agree that all men with metastatic prostate cancer should undergo germline testing and recommendations are evolving across the rest of the disease spectrum. New in 2021, the NCCN guidelines recommended germline testing for men with high and very high […]

APCCC 2021: Novel and Not So Novel Agents and Where To Place Them in the Treatment Sequence for Prostate Cancer

(UroToday.com) The third and final session of the Advanced Prostate Cancer Consensus Conference 2021 which was hosted virtually in the context of the COVID-19 pandemic focused on molecular characterization of both tissue and blood, with a focus on implications for treatment with PARP inhibitors and beyond. In the final talk of this session, Dr. Eric Small […]

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