(UroToday.com) In this session, Dr. Dana Rathkopf discusses germline testing recommendations for men with prostate cancer. Guidelines agree that all men with metastatic prostate cancer should undergo germline testing and recommendations are evolving across the rest of the disease spectrum. New in 2021, the NCCN guidelines recommended germline testing for men with high and very high risk localized prostate cancer and to consider testing for men with intermediate risk and intraductal/cribriform carcinoma.