Urodynamic effectiveness of a beta-3 adrenoreceptor agonist (vibegron) for a pediatric patient with anticholinergic-resistant neurogenic detrusor overactivity: a case report.

Myelomeningocele, which causes a neurogenic bladder, is usually treated with anticholinergics in children with neurogenic detrusor overactivity (NDO); however, anticholinergics cause side effects such as dry mouth, constipation, attention deficit, and inadequate reduction in detrusor leak point pressure.

Journal Club prostate cancer – Chris Wallis Zach Klaassen (Flatiron Health Database) – 2019

Christopher Wallis: Hello, and thank you for joining us for UroToday journal club. Today we’re discussing a recently published paper examining treatment patterns and outcomes in patients with metastatic castrate-resistant prostate cancer in a real-world practice setting in the United States. I’m Chris Wallis, a fellow in urological oncology at Vanderbuilt. With me today is […]

ASCO GU 2021: The CLEAR Study of Lenvatinib Plus Pembrolizumab or Everolimus vs Sunitinib and the SWOG 1500 Trial of Sunitinib, Cabozantinib, Crizotinib, and Savolitinib in Advanced Kidney Cancer: Discussion

(UroToday.com) Following presentations by Dr. Robert Motzer discussing results of the CLEAR study of lenvatinib plus pembrolizumab or everolimus versus sunitinib in first-line treatment of advanced renal cell carcinoma and by Dr. Sumanta Pal looking at the SWOG 1500 trial of sunitinib, cabozantinib, crizotinib, and savolitinib in patients with metastatic papillary renal cell carcinoma, Dr. Stephanie Berg […]

ASCO GU 2021: MK-6482 in Patients with Patients with Clear Cell Renal Cell Carcinoma: Discussion

(UroToday.com) Following presentations by Dr. David Bauer discussing phase I/II data for the oral HIF-2 α inhibitor MK-6482 in patients with advanced clear cell renal cell carcinoma and by Dr. Toni Choueiri looking at the combination of MK-6482 and cabozantinib in patients with previously treated clear cell renal cell carcinoma, Dr. Braun provided a discussion of […]

ASCO GU 2021: 177Lu-PSMA-617 (LuPSMA) Versus Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer Progressing After Docetaxel: Updated Results Including Progression-Free Survival and Patient-Reported Outcomes (TheraP ANZUP 1603)

(UroToday.com) The field of advanced prostate cancer has rapidly progressed over the past 15 years. Prior to the publication of TAX-327, there were no proven life-prolonging therapies for patients with metastatic castration-resistant prostate cancer (mCRPC). Since that time, there have been many new agents that have proven survival benefits including taxane-based chemotherapy, agents targeting the androgen […]

ASCO GU 2021: Biomarker Analysis from a Randomized Phase II Study of Olaparib with or Without Cediranib in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC)

(UroToday.com) The field of advanced prostate cancer has rapidly progressed over the past 15 years. Prior to the publication of TAX-327, there were no proven life-prolonging therapies for patients with metastatic castration-resistant prostate cancer (mCRPC). Since that time, there have been many new agents that have proven survival benefits including taxane-based chemotherapy, agents targeting the androgen […]

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