The aim of this cross-sectional study is to evaluate the “real life” data of patients following successful treatment with PTNS for overactive bladder syndrome (OAB) or non-obstructive voiding dysfunction (NOVD) at a 7-year follow- up after the procedure.

Patients who were successfully treated with PTNS for OAB or NOVD between February 2008 and January 2009 were contacted for a telephonic interview seven years after the end of their PTNS stimulation protocol. Patients who agreed to the interview were asked to complete a global response assessment (GRA). Patients in the OAB category completed the OAB short-form questionnaire Symptom Bother Scale (OAB-q SF) and the OAB Health-Related Quality of Life Scale (OAB HRQL), and NOVD patients were evaluated using the International Prostate Symptom Score – voiding questions (v-IPSS). Results of both questionnaires were compared with those obtained seven years previously, at the time of the initial PTNS treatment.

Seventeen patients were identified in our database. Sixteen agreed to the interview, but the remaining patient was unreachable and was therefore considered as lost at follow-up. Eight patients were classified into the OAB group, and eight were classified into the NOVD group. No patient reported a worsening condition after PTNS. Six of the eight patients (75%) in the OAB group gave positive responses in the GRA. All patients in the NOVD group gave positive responses in the GRA.

Despite some limitations, this study shows that the majority of patients who responded to PTNS considered themselves still improved at a seven- year follow-up. Larger studies are needed to confirm our results, but our study has the novel advantage of showing data derived from “real life” over the longest follow- up yet considered in the literature.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology. 2019 Sep 04 [Epub ahead of print]

Daniele Bianchi, Valerio Iacovelli, Isabella Parisi, Filomena Petta, Gabriele Gaziev, Luca Topazio, Pierluigi Bove, Giuseppe Vespasiani, Enrico Finazzi Agrò

Urology Department, Policlinico Tor Vergata, Rome, Italy – ., Department of Experimental Medicine and Surgery, Tor Vergata University, Rome, Italy., Neuro-Urology Unit, IRCCS Santa Lucia, Rome, Italy., Urology Department, Policlinico Tor Vergata, Rome, Italy.