The oncological benefit of pelvic lymph node dissection (PLND) is still debatable because data on clinical outcomes of radical prostatectomy (RP) without PLND are lacking. In this study, we reported oncological outcome in consecutive 146 patients who underwent RP without PLND. Although 27% of our patients developed biochemical recurrence, the estimated 5-year overall survival rates were 100%, 96.3%, and 95.7% in the low-, intermediate-, and high-risk groups, respectively. These data in our patients were not inferior to those in previous reports that investigated the survivals in patients who received PLND during RP. The therapeutic significance of PLND should be re-evaluated.

Cancer investigation. 2019 Oct 10 [Epub ahead of print]

Ikko Tomisaki, Hirofumi Ikuta, Katsuyoshi Higashijima, Rei Onishi, Akinori Minato, Naohiro Fujimoto

Department of Urology, University of Occupational and Environmental Health , Kitakyushu City , Japan.